DS-BIOAT Reciprocating Cylinder

Product Information

Dissolution System Dissolution System-DS BIOAT Automatic Reciprocating Cylinder- is a dissolving testing to pharmaceutical laboratories, made easier. The integration of a reciprocating cylinder dissolution system and a fully automated sampling workstation conveniently meets all requirements of major pharmacopoeias like USP, Chinese Pharmacopoeia, and European Pharmacopoeia.

The system contains a hollow transparent cylinder, which is mesh-fined on the two extremities, samples are placed within, heads sealed and turned to be reciprocated in controlled gentle up-and-down motion through dissolution medium- with this motion combined with the added shear forces induced, as the medium flows through the system, closely mimicking the actual drug dissolution process. Therefore, it is ideal for studying sustained release, targeted release, and enteric-coated formulations.

The Key Features at a Glance

🔹 Pharmacopoeia-Compliant Setup

  • 300ml glass dissolution cups

  • 7 positions, 6-row configuration

  • Fully aligned with pharmacopeial standards

🔹 Stable & Consistent Performance

  • The connecting rod structure ensures a fixed, repeatable reciprocating stroke

  • Ideal for producing consistent results, especially for low-solubility drugs

🔹 Flexible pH Simulation

  • Built to handle automatic media switching for multiple environments

  • Great for mimicking changes in human pH conditions

🔹 Efficient & Eco-Friendly

  • Uses less dissolution media

  • Easy pH changes with high correlation to bioavailability data

🔹 Advanced Filtration System

  • Combines two-stage filtration and 0.45μm membrane technology

  • Prevents adsorption issues, allowing clean, consistent sample flow

  • Maintains stable pressure throughout the process

🔹 User-Friendly Touchscreen Interface

  • 8.4-inch intuitive display

  • Human-centered design for easy navigation

  • Can store 1,000 user accounts and 1,000 test methods

🔹 Smart Data Management

  • Paperless reporting

  • USB and network backups

  • Audit tracking, role-based access, and full FDA 21 CFR Part 11 compliance

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